伊丽莎白·诺伊费尔德1928—

生平

诺伊费尔德有俄国犹太人血统，1940年时为了逃避纳粹迫害，与其俄籍犹太家属从巴黎移民至美国；在纽约安置后，诺伊费尔德先后就读亨特学院校园学校与皇后学院，并在1948年从皇后学院获得科学学士。毕业后，诺伊费尔德于缅因州巴尔港杰克逊实验室担任研究助理，研究小鼠的血液系统疾病。诺伊费尔德后来就读加州大学柏克莱分校，研究核苷酸和复合式碳水化合物，并于1956年获得博士学位。

诺伊费尔德的研究后来受到广泛地认同，由于她对溶小体储积症的论证及其基础理论等应用科学研究，做出极大的贡献，先后获得沃尔夫奖、拉斯克临床医学研究奖，并在1994年获得美国国家科学奖章。

诺伊费尔德自1984年起担任加州大学洛杉矶分校生物化学系系主任，并在2004年退休。

奖项与荣耀

1975年，诺伊费尔德获得迪克森奖医学奖。

1982年，诺伊费尔德因研究溶小体储积症引起的症状，获得拉斯克临床医学研究奖。同年，诺伊费尔德获得威廉艾伦特别贡献奖。

1984年，诺伊费尔德因研究黏多糖贮积症，获得克瑞森奖章。

1988年，诺伊费尔德与昂利·厄尔因对溶小体储积症研究，共同获得沃尔夫医学奖。

1994年，诺伊费尔德获得美国国家科学奖章生物学奖。

Elizabeth Fondal Neufeld (born September 27, 1928) is a French-American geneticist whose research has focused on the genetic basis of metabolic disease in humans.

Life

Neufeld and her Russian Jewish family emigrated to the United States from Paris in 1940; they had left Europe as refugees to escape Nazi persecution, after receiving transit visas from the Portuguese consul, Aristides de Sousa Mendes. The family settled in New York, where she attended Hunter College High School before graduating from Queens College in 1948 with a Bachelor of Science. She went on to work as a research assistant at the Jackson Laboratory in Bar Harbor, Maine, looking at blood disorders in mice. Later on, she attended graduate school at University of California, Berkeley, where she earned a Ph.D. in 1956 for her work on nucleotides and complex carbohydrates.

Neufeld has been widely recognized for her contributions to science. She is a member of the National Academy of Sciences and the American Philosophical Society. She was elected to the American Academy of Arts and Sciences in 1977. Neufeld has been awarded the Wolf Prize, the Albert Lasker Award for Clinical Medical Research, and was awarded the National Medal of Science in 1994 "for her contributions to the understanding of the lysosomal storage diseases, demonstrating the strong linkage between basic and applied scientific investigation." Neufeld was a biochemist researcher at the National Institute of Health studying mucopolysaccharidosis disorders, a group of lysosomal storage disorders in which mucopolysaccharides cannot be metabolized properly in the body. Her work showed that the genetic defects observed in Hunter and Hurler syndrome are due to a degradation of mucopolysaccharides. Neufeld's work helped advance the treatment of Hurler and Hunter syndrome.

In 1973, Neufeld became chief of NIH section of Human Biochemical Genetics, and in 1979, she became the chief of the Genetics and Biochemistry branch of National Institute of Arthritis, Diabetes, and Digestive and Kidney Diseases (NIADDK). Neufeld retired in 2004 from UCLA as Chair of the Department of Biological Chemistry, a position she occupied since 1984.

Personal life

Elizabeth Fondal married Benjamin S. Neufeld in 1951; they had two children together.