查尔斯·迪纳雷罗1943—

迪纳雷罗于在耶鲁大学1969年获得医学博士学位，自1996年在科罗拉多州大学医学院任医学教授。 他被认为是细胞因子的纯化和复制白细胞介素-1的开创者之一。于2020年获唐奖生技医药奖。

Charles A. Dinarello (born April 22, 1943) is a professor of medicine at the University of Colorado at Denver. He is an expert on inflammatory cytokines, specifically Interleukin 1 and other members of the Interleukin 1 Family of cytokines and receptors.

Education and career

Dinarello received his Doctor of Medicine in 1969 at Yale University and since 1996, he is professor of medicine at University of Colorado School of Medicine. He is also Professor of Experimental Medicine atqq3 the Radboud University Medical Center in Nijmegen, The Netherlands. Dinarello is considered one of the founding fathers of cytokines having purified and cloned interleukin-1. This important step established the validation of cytokines as mediators of disease, particularly of inflammation. Current studies blocking IL-1 in humans supports Dinarello's and his co-workers pivotal contributions to cytokine biology and the pathogenesis of inflammatory diseases.

He is fluent in English, Italian and German.

Awards

1993: Ernst Jung Prize

2006: Hamdan Award for Medical Research Excellence, awarded by Sheikh Hamdan bin Rashid Al Maktoum Award for Medical Sciences, Dubai, United Arab Emirates

2009: Crafoord Prize in Polyarthritis (together with Tadamitsu Kishimoto and Toshio Hirano) “for their pioneering work to isolate interleukins, determine their properties and explore their role in the onset of inflammatory diseases”.

2009: Albany Medical Center Prize (shared with Ralph M. Steinman and Bruce A. Beutler)

2010: Paul Ehrlich and Ludwig Darmstaedter Prize

2010: Novartis Prize in Clinical Immunology (together with Juerg Tschopp).

2011: Foreign membership of the Royal Netherlands Academy of Arts and Sciences

2020: Tang Prize in Biopharmaceutical Science.