亚历山大·鲁登斯基1956—

职业生涯

鲁登斯基于1986年获莫斯科加布里切夫斯基流行病学与微生物学研究所科学副博士学位，并于耶鲁大学医学院完成博士后研究。现任纪念斯隆-凯特琳癌症中心免疫学项目主席暨路德维希研究中心主任，同时兼任洛克菲勒大学、康乃尔大学、格斯特纳研究生院及威尔康奈尔医学院教授。

在2003年发表的一篇论文中，鲁登斯基与研究团队证实FOXP3基因主导调节T细胞的发育过程。其实验室持续深入探究调节T细胞活性的分子机制，以及这些细胞在自体免疫、肿瘤免疫与感染免疫中扮演的角色。

荣誉

• 美国国家科学院院士（2012年）
• 美国文理科学院院士（2015年）
• 威廉·B·科莱奖（2015年）
• 克拉福德奖（2017年）
• 维尔切克奖（2018年）

Alexander Rudensky (born August 21, 1956) is an immunologist at Memorial Sloan Kettering Cancer Center known for his research on regulatory T cells and the transcription factor FOXP3.

Career

Rudensky received his Candidate of Sciences degree in 1986 from the Gabrichevsky Research Institute of Epidemiology and Microbiology, Moscow, and completed his postdoctoral work at the Yale School of Medicine. He is now the Chair of the Immunology Program and Director of the Ludwig Center at Memorial Sloan Kettering, as well as a professor at the Rockefeller University, Cornell University, Gerstner School of Graduate Studies, and Weill-Cornell Medical School.

In a 2003 paper, Rudensky and colleagues showed that FOXP3 programs regulatory T cell development. His lab continues to investigate the molecular mechanisms underlying regulatory T cell activity, and the role these cells play in autoimmunity, tumor immunity, and immunity to infections.

Awards

• 2012 Member of the National Academy of Sciences
• 2015 Member of the American Academy of Arts and Sciences
• 2015 William B. Coley Award
• 2017 Crafoord Prize in Polyarthritis
• 2018 Vilcek Prize in Biomedical Science